The fifth meeting in the successful seriesHelicobacter pylori: Basic Mechanisms to Clinical Curetook place in Maui, Hawaii, November 2002. The meeting focused on all current aspects ofH. pyloriresearch. Internationally acclaimed basic and clinical researchers explored, in depth, the novel information across the spectrum ofH. pyloriinfection, the characteristics of the organism, the inflammatory and tissue modifying consequences, the overall impact of this infection on a global scale, and new therapeutic possibilities.
H. pyloriinfection, both in man and in the laboratory animal, has become a standard model to investigate fundamental problems in biology, such as microbial-host interactions, intracellular signalling, modulation of inflammation, mucosal atrophic metaplasia, and microbial resistance, to name just a few. The issues addressed in this book are grouped according to their leading theme. Topics include: the new Helicobacters, strain differences ofH. pyloriand their consequence on microbial-host interactions and the effects ofH. pyloriinfection on the gastric mucosa. The role ofH. pyloriis explained in relation to: gastric carcinogenesis; gastroesophageal reflux disease; dyspepsia and long-term acid suppression. Eradication therapies are reviewed with respect to their global consequences and problems. The last two sections are devoted to a global update on therapeutic indications and finally on priorities for further research.
These proceedings accurately reflect the state-of-the-art presentations delivered by world experts. This latest volume will further enrich this top-class series onH. pyloriinfection.

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